Table 3 |
|||||||
|
Survival analysis for rs12425791 and rs11833579 and risk of death or stroke recurrence among first-ever ischemic stroke patients |
|||||||
|
SNP |
Neither death nor stroke recurrence observed (n = 706) |
Either Death or stroke recurrence (n = 59) |
|||||
|
|
|||||||
|
No. |
(%) |
No. |
(%) |
HR* (95% CI) |
P-value |
q-value‡ |
|
|
|
|||||||
|
rs12425791 |
|||||||
|
GG |
421 |
(93.1) |
26 |
(5.8) |
1.0† |
||
|
GA |
244 |
(90.7) |
24 |
(9.0) |
1.55(0.88-2.74) |
0.131 |
0.149 |
|
AA |
41 |
(82.0) |
9 |
(18.0) |
3.30(1.53-7.12) |
0.002 |
0.018 |
|
GG |
421 |
(94.2) |
26 |
(5.8) |
1.0 |
||
|
GA+AA |
285 |
(89.6) |
33 |
(10.4) |
1.83(1.08-3.08) |
0.024 |
0.038 |
|
GG+GA |
665 |
(93.0) |
50 |
(7.0) |
1.0 |
||
|
AA |
41 |
(82.0) |
9 |
(18.0) |
2.76(1.34-5.68) |
0.006 |
0.018 |
|
rs11833579 |
|||||||
|
GG |
319 |
(94.4) |
19 |
(5.6) |
1.0† |
||
|
GA |
299 |
(92.0) |
26 |
(8.0) |
1.53(0.84-2.80) |
0.164 |
0.164 |
|
AA |
86 |
(86.0) |
14 |
(14.0) |
2.68(1.31-5.48) |
0.007 |
0.018 |
|
GG |
319 |
(94.4) |
19 |
(5.6) |
1.0 |
||
|
GA+AA |
385 |
(90.6) |
40 |
(9.4) |
1.80(1.03-3.13) |
0.039 |
0.052 |
|
GG+GA |
618 |
(93.2) |
45 |
(6.8) |
1.0 |
||
|
AA |
86 |
(86.0) |
14 |
(14.0) |
2.15(1.15-4.02) |
0.017 |
0.034 |
|
|
|||||||
|
*: Adjusted for age, gender, hypertension, diabetes mellitus, cigarette smoking and alcohol drinking, obesity, and NIHSS at the beginning †: p for trend < 0.05 ‡: False discovery rate (FDR) was controlled using the Benjamini-Hochberg procedure |
|||||||
|
Hsieh et al. Journal of Biomedical Science 2012 19:1 doi:10.1186/1423-0127-19-1 |
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