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Calcium-sensing receptors regulate cardiomyocyte Ca2+ signaling via the sarcoplasmic reticulum-mitochondrion interface during hypoxia/reoxygenation

Fang-hao Lu1†, Zhiliang Tian2†, Wei-hua Zhang1,5*, Ya-jun Zhao1, Hu-lun Li3, Huan Ren4, Hui-shuang Zheng1, Chong Liu1, Guang-xia Hu1, Ye Tian1, Bao-feng Yang5, Rui Wang6 and Chang-qing Xu1,5*

1 Department of Pathophysiology, Harbin Medical University, Harbin 150086, China

2 Department of Pediatrics, the second affiliated Hospital of Harbin Medical University, Harbin 150086, China

3 Department of Neurobiology, Harbin Medical University, Harbin 150086, China

4 Department of Immunology, Harbin Medical University, Harbin 150086, China

5 Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin Medical University, Harbin 150086, China

6 Department of Biology, Lakehead University, Thunder Bay, Ontario, P7B5E1, Canada

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Journal of Biomedical Science 2010, 17:50 doi:10.1186/1423-0127-17-50

Published: 17 June 2010

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Additional file 1:

CaR inducing apoptosis via the sarcoplasmic reticulum-mitochondrion crosstalk in hypoxia/reoxygenation.

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