The cost of publication in Journal of Biomedical Science is borne by the National Science Council, Taiwan.
Research
Genetic copy number variants in sib pairs both affected with schizophrenia
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* Corresponding author: Hai-Gwo Hwu haigohwu@ntu.edu.tw
- † Equal contributors
1 National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan
2 Department of Psychiatry, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
3 Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Taiwan
4 Department of Psychology, College of Science, National Taiwan University, Taipei, Taiwan
Journal of Biomedical Science 2010, 17:2 doi:10.1186/1423-0127-17-2
Published: 11 January 2010Additional files
Additional file 1:
Supplementary table 1. Information of the primers for real-time PCR.
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Additional file 2:
Supplementary table 2. Comparison of incidence of CNVs in schizophrenics and in control subjects.
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Additional file 3:
Supplementary figure 1. The quantitative real-time PCR (QPCR) results for potential candidate genes identified by array CGH. The fold change in gene copy number for each indicated target gene relative to the endogenous reference gene (ATP2B4) was compared for the genomic DNA samples from affected sib pairs with at least one showing positive results by array CGH. The fold change for each target gene and ATP2B4 of control sample was set at 1. The normalized fold changes were interpreted as follows: No change (0.7-1.4, white bar), homozygous loss (< 0.3, black bar), over representation (> 1.4, black bar) and ambiguous (0.3-0.7, gray bar).
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