Table 1

Fetal loss and cardiac abnormality in NaVP exposed dams

Treatment (Gestation)

No. of dams

Total No. of

Live fetuses (fetus/dam)

N. of death or resorption

Cardiac abnormalities

No. in live fetus

%

Day 6

Control

10

163 (16.3)

2

1

0.60

Treated

20

148 (7.4)*

63*

13

8.70*

Day 7

Control

12

148 (12.3)

3

1

0.67

Treated

24

162 (6.75)*

90*

34

20.90*

Day 8

Control

10

147 (14.7)

3

0

0.00

Treated

20

132 (6.6)*

78*

13

9.80*

Day 9

Control

10

149 (14.9)

1

1

0.68

Treated

20

142 (7.1)*

60*

9

6.30*

Pregnant female mice received a one-time injection (i.p.) of NaVP (700 mg/kg body weight) on gestation day as indicated. The fetuses were examined on gestation day 19 after sacrifice of the pregnant mice as described in Materials and Methods.

* P < 0.05 compared to controls.

Wu et al. Journal of Biomedical Science 2010 17:16   doi:10.1186/1423-0127-17-16