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Amino acid residues 201-205 in C-terminal acidic tail region plays a crucial role in antibacterial activity of HMGB1

Wei Gong* email, Yuan Li* email, Fan Chao email, Gang Huang email and Fengtian He email

Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Third Military Medical University, Chongqing, PR China

author email corresponding author email* Contributed equally

Journal of Biomedical Science 2009, 16:83doi:10.1186/1423-0127-16-83

Published: 14 September 2009

Additional files

Additional file 1:

Antibacterial efficiency analysis of the recombinant proteins and C peptide by dispersion method (diameter/mm). The antibacterial activities of the recombinant proteins and C peptide were detected by dispersion method as described in Materials and Methods. The numbers refers to the diameters (mm) of the antibacterial cirques showed in the table. The zone without bacterial growth reflects the potency of growth inhibition. DHFR was used as a negative control.

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